Vitamin K2 supplement tested as new migraine treatment

NCT ID NCT05943457

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking vitamin K2 supplements daily for 6 months can reduce the number of migraine days in adults with episodic migraine. Researchers will also measure if it improves artery stiffness, which is often higher in people with migraines. 160 participants will be randomly assigned to receive either vitamin K2 or a placebo pill.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vitamin K2 (menaquinone-7) supplement

What this could lead to

If it works, this could offer a simple, low-cost supplement to reduce migraine frequency and improve blood vessel health.

What could go wrong

This is an early-stage trial with 160 people, so results may not apply to everyone. Supplements can have side effects, and the benefit over placebo may be small or none.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

migraine disorder vitamin K deficiency hemorrhagic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lebanese American University Medical Center - Rizk Hospital

    RECRUITING

    Beirut, Beirut, 11-3288, Lebanon

    Contact Phone: •••-•••-•••• Email: •••••@•••••