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Aneurysm repair may stiffen arteries — a study asks what that means for the heart

NCT ID NCT07722793

Knowledge-focused Sponsor: Josip Juraj Strossmayer University of Osijek Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 23, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study follows 60 people with abdominal aortic aneurysm who are scheduled for endovascular repair (EVAR). Researchers will measure artery stiffness, heart structure and function, and certain blood markers before the procedure and at several points afterward. The goal is to understand how EVAR affects the cardiovascular system and whether these changes matter for long-term heart health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study clarifies how EVAR affects the heart and arteries, it could help doctors better manage long-term cardiovascular risk after the procedure.
What could go wrong
This is an observational study, not a treatment trial, so it will not test a new therapy. The results may show changes but cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with abdominal aortic aneurysm (AAA) scheduled for elective endovascular aneurysm repair (EVAR) will be prospectively enrolled. The study population will include patients undergoing standard-of-care EVAR, who will be followed longitudinally to assess changes in arterial stiffness, cardiac function, and circulating biomarkers before and after the procedure.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (≥18 years of age) with diagnosed abdominal aortic aneurysm (AAA) who are scheduled for elective endovascular aneurysm repair (EVAR) * Patients eligible for EVAR according to current clinical guidelines and anatomical criteria * Signed informed consent for participation in the study * Ability to undergo scheduled follow-up examinations (baseline, early post-procedural assessment, and follow-up visits) Exclusion Criteria: * Emergency EVAR for ruptured or symptomatic abdominal aortic aneurysm * Previous aortic repair or previous endovascular intervention involving the abdominal aorta * Concomitant major cardiovascular surgery or intervention during the study period * Severe hemodynamic instability or critical illness at the time of inclusion * Active infection or acute inflammatory disease that may influence vascular or inflammatory biomarkers * Malignancy with active treatment or life expectancy limiting follow-up * Inability to provide informed consent * Inability to complete planned follow-up assessments * Known severe valvular heart disease or advanced heart failure * Conditions affecting arterial stiffness measurements (e.g. atrial fibrillation, severe arrhythmias, inability to obtain reliable PWV measurements)

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Conditions

The condition(s) this trial relates to.

abdominal aortic aneurysm Ventricular Remodeling

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal aortic aneurysm Arterial stiffness Left ventricle remodeling

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Vascular Surgery, University Hospital Center Osijek

    Osijek, 31000, Croatia

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