ABDOMINAL AORTIC ANEURYSM

This study tests whether specially modified grafts can safely repair complex aortic aneurysms in patients who are too high-risk for standard surgery. About 220 participants with abdominal or thoracoabdominal aneurysms or aortic dissections will receive a physician-modified endova…

This study is a global registry that will follow about 1,000 people who receive a Terumo aortic graft to treat an aneurysm in the chest or abdomen. Researchers will track how well the graft works and how safe it is over time, including deaths related to the aorta. The goal is to …

This early study tests a new device (Cygnum) placed inside the aneurysm sac during standard stent-graft repair for abdominal aortic aneurysms. The goal is to see if it is safe and can prevent blood leaks (type II endoleaks) that can cause the aneurysm to grow. About 15 adults wit…

This study is a registry that will collect data from about 200 people in Italy and Poland who receive a special stent-graft called PERCUTEK Tycheseal to treat an abdominal aortic aneurysm (a bulging weak spot in the main belly artery). The goal is to see how well the device works…

This study compares two medical devices (Endurant and Excluder stent grafts) used to treat abdominal aortic aneurysms—a bulging blood vessel in the belly. About 600 people with large aneurysms will be randomly assigned to receive one of the two devices. The main goal is to see wh…

This study compares two ways to treat complex aortic aneurysms (a bulging blood vessel in the belly). One method uses a custom-made stent-graft, and the other uses a stent-graft shaped with the help of a 3D-printed model of the patient's aorta. The goal is to see which approach l…

This study tests a new treatment called the Nectero EAST system for people with small to medium-sized abdominal aortic aneurysms (AAA). The goal is to see if a single treatment delivered inside the blood vessel can stabilize the aneurysm and prevent it from growing or rupturing. …

This study compares two ways to screen men at high risk for abdominal aortic aneurysm (AAA): having their general practitioner use a small, portable ultrasound device during a regular visit versus the current standard of referring them to a radiologist. The goal is to see if the …

This study tests whether placing metal coils inside the aneurysm sac during standard endovascular repair can prevent type II endoleaks—a common complication where blood flows backward into the aneurysm. About 100 people with large abdominal aortic aneurysms and a high risk of thi…

This study at Mayo Clinic aims to test two new imaging methods to measure the strength and movement of the aorta, the body's main artery. Researchers will compare results from 30 people with and without an abdominal aortic aneurysm. The goal is to better understand how the aorta …

This early-phase study tests a new radioactive tracer called [64Cu]-RYM2 in PET/CT scans to see if it can safely detect enzyme activity (MMP) in abdominal aortic aneurysms (AAA). Researchers will compare scans from 28 healthy volunteers and AAA patients scheduled for surgery. The…