Nerve block may offer safer pain relief after major aortic surgery

NCT ID NCT06244732

Recruiting now Symptom relief Sponsor: IRCCS Policlinico S. Donato Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether a nerve block (rectus sheath block) can control pain after open abdominal aortic aneurysm repair as well as the standard epidural analgesia, but with fewer complications. About 60 adults undergoing elective surgery will be randomly assigned to one of the two pain management methods. Researchers will measure pain levels and track any side effects or need for extra pain medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: rectus sheath block (nerve block)
What this could lead to: If the nerve block works as well as epidural analgesia with fewer side effects, it could offer a simpler, safer way to manage pain after this major surgery.
What could go wrong: This is a small, early-stage study with only 60 participants, so results may not apply to all patients. The nerve block might not control pain as effectively as the standard epidural approach.

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Conditions

The condition(s) this trial relates to.

abdominal aortic aneurysm Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL AORTIC ANEURYSM POSTOPERATIVE PAIN

Contacts and locations

Locations

I.R.C.C.S. Policlinico San Donato
RECRUITING

San Donato Milanese, Milan, 20097, Italy

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