Irccs Policlinico S. Donato

This study aims to monitor the real-world performance and safety of the Navitor transcatheter aortic valve in 1000 patients with severe, symptomatic aortic stenosis. Participants will receive the valve implant as part of their standard care and be followed for five years to track…

This study is collecting real-world data on the safety and effectiveness of the JenaValve Trilogy™ System, a new device for replacing a leaky aortic heart valve without major surgery. It will follow 75 patients with severe aortic regurgitation who are at high risk for traditional…

This study aims to develop a better, more accessible way to detect Alzheimer's disease in its earliest stages. Researchers will enroll 250 adults who have subjective memory concerns but are otherwise functioning normally. They will combine data from blood tests, speech recordings…

This large study aims to find better ways to predict who is at risk for heart disease. It will test whether adding genetic testing or heart imaging to standard risk calculations helps people lower their risk more effectively. About 30,000 healthy Italian adults will receive perso…

This study analyzes tissue removed during aortic aneurysm surgery to measure how strong it is and how likely it is to rupture. Researchers will test 40 patients' aortic tissue in a lab to understand its properties. The goal is to help doctors better predict which aneurysms need s…

This study aims to develop and test new AI software that automatically analyzes 3D ultrasound scans of the heart's mitral valve. The software will create detailed 3D models to measure the valve's shape and simulate the effects of surgical repair. Researchers will enroll 150 adult…

This study aims to better understand aortic stiffness in people with genetic conditions that affect the aorta, the body's main artery. Researchers will measure stiffness using a simple, non-invasive test called Pulse Wave Velocity in 250 participants who have thoracic aortic aneu…

This study aims to understand how lifestyle, stress, and other personal factors affect people living with genetic aortic diseases. Researchers will survey 208 Italian-speaking adults with these conditions to learn about their journey to diagnosis, quality of life, and overall wel…

This study aims to develop and test new software that makes heart MRI scans easier to analyze. Researchers want to create automated tools that can measure blood flow and pressure inside the heart without invasive procedures. The study involves patients with severe aortic valve na…