Scientists probe mystery gene's role in heart disease

NCT ID NCT06230406

Recruiting now Knowledge-focused Sponsor: IRCCS Policlinico S. Donato Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a gene called TMEM230 plays a role in atherosclerosis, the buildup of fatty plaques in arteries that can lead to heart attacks and strokes. Researchers will collect blood and artery tissue from 12 adults undergoing vascular surgery. They aim to understand how this gene is turned on or off in diseased arteries, which could eventually lead to new prevention or treatment strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward new targets for preventing or treating atherosclerosis, potentially reducing heart disease and stroke.
What could go wrong: This is a very small, early-stage observational study (12 participants) focused on understanding basic biology, not testing a treatment. Results may not lead directly to therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atherosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATHEROSCLEROSIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

I.R.C.C.S. Policlinico San Donato
RECRUITING

San Donato Milanese, Milan, 20097, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••

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