Skin cells hold clues to deadly aneurysm risk

NCT ID NCT07282717

Summary

This study aims to understand why some adults with a specific gene mutation (COL5A) develop dangerous bulges in their main heart artery (aortic aneurysms), while others with the same mutation do not. Researchers will collect small skin samples from 20 participants to grow and study their skin cells, looking for differences in how they produce and organize collagen. The goal is to identify biological markers that could explain this variation in risk and help guide future personalized monitoring approaches.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cardiovascular Genetic Centre IRCCS Policlinico San Donato

    San Donato Milanese, Italy, 20097, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.