Simple Pre-Surgery trick may shield kidneys from damage

NCT ID NCT07441564

Not yet recruiting Disease control Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a short, controlled clamping of the aorta before aneurysm surgery can prevent acute kidney injury. About 206 patients will be randomly assigned to receive this preconditioning or standard care. The goal is to see if this simple procedure lowers the risk of kidney damage after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ischemic preconditioning (brief clamping of the aorta before surgery)
What this could lead to: If it works, this could offer a simple way to protect kidneys during high-risk aneurysm surgery, reducing complications and improving recovery.
What could go wrong: This is an early human test of a technique never tried in people before. It may not reduce kidney injury, and the clamping itself carries some risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal aortic aneurysm aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEURYSM AORTIC

Contacts and locations

Locations

Ap-Hp La Pitie

Paris, 75013, France
CHU de DIJON

Dijon, 21000, France
CHU de LILLE

Lille, 59000, France
CHU de NANCY

Nancy, 54511, France
CHU de NANTES

Nantes, 44093, France
CHU de ROUEN

Rouen, 76031, France
CHU de TOULOUSE

Toulouse, 31400, France

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