New valve offers hope for leaky heart patients too frail for surgery

NCT ID NCT07075861

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a device called JenaValve Trilogy to replace the aortic valve without open-heart surgery in 75 people with severe aortic regurgitation (a leaky heart valve). Participants are at high risk for surgery. The main goal is to see if the device works safely and stays in place after 12 months, reducing the risk of death and complications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Policlinico San Donato

    RECRUITING

    San Donato Milanese, Milano, 20097, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Other studies related to the condition(s) this trial covers.