New heart valve offers hope for High-Risk patients without open surgery

NCT ID NCT07075861

First seen Nov 18, 2025 · Last updated May 18, 2026 · Updated 29 times

Summary

This study is testing a new device called the JenaValve Trilogy to replace the aortic valve in people with severe aortic regurgitation (a leaky heart valve) who are too high-risk for open-heart surgery. About 75 participants will receive the valve through a tube in an artery, avoiding major surgery. Researchers will check if the valve works well and is safe after 12 months, focusing on survival and avoiding complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Policlinico San Donato

    RECRUITING

    San Donato Milanese, Milano, 20097, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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