Lab and body tests aim to find best heart valve for small aortic openings

NCT ID NCT06859255

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study compares different types of heart valve prostheses used to treat severe aortic stenosis in people with a small aortic annulus. Researchers will test the valves in the lab and then in patients using echocardiograms and a special MRI scan that measures blood flow. The goal is to see which valves and surgical techniques work best for this specific group of patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could help doctors choose the best valve type and implantation technique for patients with a small aortic annulus, potentially improving long-term outcomes.

What could go wrong

This is an observational study without a new treatment, so it will not directly benefit participants. The findings may not apply to all patients or valve models.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • IRCCS Policlinico San Donato

    RECRUITING

    San Donato, Lombardy, 20097, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Policlinico di Bari

    RECRUITING

    Bari, Apulia, 70100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact