Lab and body tests aim to find best heart valve for small aortic openings

NCT ID NCT06859255

Recruiting now Knowledge-focused Sponsor: IRCCS Policlinico S. Donato Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study compares different types of heart valve prostheses used to treat severe aortic stenosis in people with a small aortic annulus. Researchers will test the valves in the lab and then in patients using echocardiograms and a special MRI scan that measures blood flow. The goal is to see which valves and surgical techniques work best for this specific group of patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help doctors choose the best valve type and implantation technique for patients with a small aortic annulus, potentially improving long-term outcomes.
What could go wrong: This is an observational study without a new treatment, so it will not directly benefit participants. The findings may not apply to all patients or valve models.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE AORTIC VALVE STENOSIS

Contacts and locations

Locations

IRCCS Policlinico San Donato
RECRUITING

San Donato, Lombardy, 20097, Italy
Policlinico di Bari
RECRUITING

Bari, Apulia, 70100, Italy

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