CT scan could guide safer blood thinner use after TAVI

NCT ID NCT06168370

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests whether a CT scan 3 months after TAVI (aortic valve replacement) can help doctors decide who needs blood thinners and who can stop them. Currently, patients take aspirin for life, which can cause bleeding. The trial will enroll 2,500 people and compare this personalized approach to standard care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Antonius Hospital

    RECRUITING

    Nieuwegein, Netherlands

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

apixaban (a blood thinner)

What this could lead to

If successful, this approach could reduce the risk of blood clots and strokes after TAVI without increasing bleeding, potentially replacing lifelong aspirin for many patients.

What could go wrong

This is a large trial but still experimental. The CT-guided strategy may not prove better than standard care, and some patients may still experience bleeding or clotting events.

Conditions

The condition(s) this trial relates to.

aortic valve stenosis Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.