New heart valve study aims to improve survival in aortic stenosis patients

NCT ID NCT07359898

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study is testing the Navitor heart valve in 1000 people with severe aortic stenosis, a condition where the heart's main valve narrows. Participants receive the valve through a catheter, and researchers track survival and complications for one year. The goal is to see how well the valve works in everyday medical practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Navitor/Navitor Vision transcatheter aortic valve
What this could lead to
If successful, this could confirm that the Navitor valve is safe and effective for treating severe aortic stenosis in a broad patient population.
What could go wrong
This is an observational study without a comparison group, so results may not prove the valve is better than other options. Risks include complications from the valve implant procedure, such as bleeding or stroke.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Policlinico San Donato

    RECRUITING

    San Donato Milanese, Lombardy, 20097, Italy