Personalizing blood thinners after carotid stenting could prevent heart attacks and strokes

NCT ID NCT05566301

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study looks at people with narrowed carotid arteries who are getting a stent. Some people do not respond well to the common blood thinner clopidogrel. The study compares giving these 'non-responders' a different drug, ticagrelor, versus continuing clopidogrel in those who respond. Researchers will track deaths, major heart events, and bleeding for up to three months after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Clopidogrel and Ticagrelor

What this could lead to

If successful, this could help doctors choose the right antiplatelet drug for each patient, potentially reducing heart attacks, strokes, and bleeding after carotid stenting.

What could go wrong

This is an observational study, not a randomized trial, so results may show associations but not prove cause. The findings may not apply to all patients or settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

carotid stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Locations

  • IRCCS Policlinico San Donato

    RECRUITING

    San Donato Milanese, Milan, 20097, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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