Custom-Made stent grafts offer hope for High-Risk aneurysm patients
NCT ID NCT04746677
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a special stent graft that doctors modify by hand to treat complex aortic aneurysms and dissections in patients who are too high-risk for standard surgery or devices. About 220 participants will be followed for up to 5 years to see if the procedure is safe and effective. The goal is to offer a less invasive option for those with few alternatives.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- physician-modified endovascular graft (PMEG)
- What this could lead to
- If successful, this could provide a safer, less invasive treatment option for high-risk patients with complex aortic aneurysms or dissections who cannot use standard devices.
- What could go wrong
- This is a single-center trial with no control group, so results may not apply broadly. Risks include stroke, kidney failure, paralysis, and other serious complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can big data unlock the secrets of a deadly aortic emergency?
- Can a tailored stent graft tame complex aortic aneurysms?
- Can sound waves replace CT scans for aortic aneurysm monitoring?
- A simple gas flush before aortic repair might prevent strokes
- Can a stent-graft keep aortic aneurysms in check for years? a long-term follow-up study aims to find out.
- Aneurysm repair may stiffen arteries — a study asks what that means for the heart