Can a tailored stent graft tame complex aortic aneurysms?
NCT ID NCT04526938
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This trial is testing a specially modified stent graft—a small mesh tube—to repair complex aortic aneurysms in people who are too high-risk for open surgery. The graft is adjusted by the physician to keep blood flowing to the kidneys and other vital organs during the procedure. The study will track safety, how well the repair holds up over a year, and how the treatment affects quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A physician-modified Cook Zenith Alpha Thoracic Endovascular Graft, a stent graft device altered to keep blood flowing to vital organs during aneurysm repair.
- What this could lead to
- If successful, this could offer a safer, less invasive repair option for people with complex aortic aneurysms who are too high-risk for open surgery, potentially improving survival and quality of life.
- What could go wrong
- This is an early-stage study focused on safety and feasibility, not a proven treatment. Risks include major complications like stroke, kidney failure, or bowel ischemia, and the modified device may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A simple gas flush before aortic repair might prevent strokes
- Customized grafts could repair dangerous aortic aneurysms without open surgery
- New stent grafts aim to fix aortic aneurysms without major surgery
- Aortic Stent-Graft safety under the microscope: 600-Patient european registry launches
- New stent device aims to fix dangerous aortic bulge without major surgery
- New Stent-Graft procedure offers hope for High-Risk aortic patients