New Stent-Graft procedure offers hope for High-Risk aortic patients

NCT ID NCT00583817

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing a less invasive procedure using stent-grafts to treat various types of aortic disease, including aneurysms and dissections. It involves 170 participants who are considered too high-risk for traditional open surgery. The goal is to see if this endovascular approach can reduce deaths and serious complications like stroke.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Endovascular stent-graft implantation (device)
What this could lead to
If successful, this could provide a less invasive treatment option for people with aortic disease who are too high-risk for open surgery.
What could go wrong
This is an early-stage, non-randomized study with no control group, so results may not prove effectiveness. Risks include stroke, death, or incomplete repair.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Aneurysm aneurysm or dilatation of ascending aorta Aneurysm, Ascending Aorta aortic aneurysm Aortic Aneurysm, Thoracoabdominal Aortic Dissection Dissection, Ascending Aorta thoracic aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

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