Medstar Health Research Institute

This study compares two types of hip implants used in total hip replacement: one with a collar and one without. The goal is to see if the collared implant reduces sinking (subsidence) and lowers the risk of fractures around the implant. About 100 adults getting a first-time hip r…

This study explores whether virtual reality (VR) can help people with cancer manage chronic pain and possibly reduce their need for opioid painkillers. Researchers will work with 25 adults who have active cancer and moderate-to-severe pain to develop and test a VR program designe…

This early-stage study tests whether a harmless bacteria called Lactobacillus crispatus, when placed directly into the bladder, is safe and can reduce urinary symptoms and infections in adults with spinal cord injury who use catheters. About 40 participants will receive two bladd…

This study is for people with neurogenic bladder (a bladder that doesn't work normally due to nerve damage) who use a permanent catheter. Researchers want to see if putting a probiotic called Lactobacillus directly into the bladder can reduce urinary symptoms and improve quality …

This study tests a prescription smartphone app called RiSolve to see if it can reduce overactive bladder symptoms in women. About 596 women with bothersome bladder issues will either use the app or receive standard educational handouts for 8 weeks. The goal is to improve symptoms…

This study tests whether taking rimegepant before a known trigger—like exercise, alcohol, or stress—can prevent a migraine from starting. About 60 adults with predictable triggers will take the drug ahead of planned activities and report if a headache occurs within 24 hours. The …

This study tests if a special vacuum dressing (closed incision negative pressure therapy) helps wounds heal better after breast reduction surgery compared to a standard bandage. About 92 women will each have one breast treated with the special dressing and the other with a standa…

This study is testing a virtual reality (VR) device that uses cognitive behavioral therapy to help people with chronic cancer pain. The goal is to see if the VR headset is easy to use, safe, and can reduce pain and distress. About 40 adults with cancer who have had pain for at le…

This study compares a new pessary system that women can insert and remove at home to standard pessary care for pelvic organ prolapse. About 200 women who have not used a pessary before will be randomly assigned to one of the two groups. The goal is to see if the new system improv…

This study looks at the experiences of 200 adults with spinal muscular atrophy (SMA) to understand why some are not receiving approved treatments. Researchers will survey patients about barriers like cost, side effects, or access issues. The goal is to identify gaps in care and h…

This study interviews 60 adults with spinal cord injuries and neurogenic bladder, plus their caregivers, to understand their experiences with different bladder washes (antibiotics, probiotics, or both). The goal is to learn what works best from the patient's perspective, not to t…