Customized grafts could repair dangerous aortic aneurysms without open surgery

NCT ID NCT06657794

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This trial tests a physician-modified stent graft to treat juxtarenal aortic aneurysms—a bulge in the aorta near the kidneys—in people who are too high-risk for open surgery. The graft is altered during the procedure to create openings that keep blood flowing to vital branch vessels. The study aims to see if the device is safe and effective in the short and long term, up to five years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Physician-Modified Terumo Aortic TREO abdominal stent graft system

What this could lead to

If successful, this approach could offer a less invasive treatment option for people with complex aortic aneurysms who are not candidates for open surgery.

What could go wrong

This is a small, early-stage study with only 15 participants, so results may not apply to everyone. Risks include graft infection, kidney failure, or aneurysm rupture.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

abdominal aortic aneurysm aortic aneurysm Aortic Rupture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

    Contact Email: •••••@•••••