Beth Israel Deaconess Medical Center

This study aims to find out if high-flow oxygen therapy works better than standard oxygen therapy for saving the lives of adults with dangerously low blood oxygen in five East African hospitals. About 1,600 participants will be randomly assigned to receive one of the two oxygen d…

This study is testing a new, non-surgical procedure to fix persistent air leaks in the lungs, a condition that can keep patients in the hospital for a long time. Doctors will combine two techniques during a standard bronchoscopy: placing a small valve to block the leak and inject…

This study is testing a new way to monitor heart devices like pacemakers and defibrillators. It compares getting care based on remote alerts from the device versus following standard checkup schedules. The goal is to see which approach is safer and more effective for patients.

This study is testing if having healthy groceries delivered to your home for a month, with help from a dietitian, can lower high blood pressure. It will compare this approach to simply giving people a guide and money to shop for themselves. The goal is to find a practical way to …

This large study aims to find the best approach for patients who have a brain bleed while taking cholesterol-lowering statin drugs. It will test whether continuing or stopping the statin medication leads to better long-term health, including fewer repeat brain bleeds or other maj…

This study aims to determine whether transferring embryos on day 3 or day 5 leads to better pregnancy outcomes for IVF patients who produce only a few embryos. Researchers will randomly assign over 1,100 first-time IVF patients with five or fewer embryos to either early (day 3) o…

This study is testing whether the drug epcoritamab can help people with follicular lymphoma whose cancer did not completely disappear after their initial treatment. The drug works by activating the immune system to attack cancer cells. About 35 adults who had a partial response o…

This trial is testing a minimally invasive procedure for patients with dangerous aortic aneurysms who are too high-risk for traditional open surgery. Doctors will modify a standard aortic graft on-site to fit each patient's unique anatomy and implant it via a small incision. The …

This study is testing whether a home device for monitoring a baby's heart rate is practical and acceptable for women with high-risk pregnancies. It aims to see if this remote monitoring can be a helpful addition to regular prenatal care, potentially reducing the need for frequent…

This study is testing whether adding a second medication (raloxifene) to a standard prostate drug (finasteride) works better for men with an enlarged prostate. It aims to help men whose symptoms don't improve enough with the standard drug alone. Researchers will also check if a s…

This small pilot study is testing whether wearing a special hat that emits infrared light can help reduce seizures in adults with drug-resistant epilepsy. All 13 participants will try the daily light therapy to see if it's safe, tolerable, and might decrease seizure frequency. Th…

This study is testing if a short, 3-day course of intravenous steroids (hydrocortisone) can help patients with severe acute pancreatitis. Researchers believe reducing the body's intense inflammatory response may prevent organ failure, shorten hospital stays, and improve survival.…

This study is testing whether a foam containing the drug roflumilast can help reduce painful lumps and abscesses in people with hidradenitis suppurativa (HS), a chronic inflammatory skin condition. About 20 adult participants with mild-to-moderate HS will apply the foam daily for…

This study is testing a new rehabilitation method for people who have lost part of their vision after a stroke. Researchers are combining gentle, non-invasive brain stimulation with visual training exercises, some using virtual reality, to see if it can help restore vision in the…

This study is testing a new decision-making tool for women aged 70 and older who have a common, low-risk type of early breast cancer. The goal is to see if giving patients a detailed guide and training their surgeons in shared decision-making leads to fewer aggressive treatments …

This study is testing whether combining two treatments can improve sleep for people aged 60+ who have both insomnia and mild memory problems. One treatment is a safe, gentle form of brain stimulation (TMS), and the other is a type of talk therapy for insomnia (CBT-I). Researchers…

This study is testing whether using a special pelvic wand for perineal massage in late pregnancy and during labor helps people feel more in control of their birth process. Researchers will compare two groups of about 140 pregnant participants: one using the wand and one receiving…

This study is testing whether training doulas (birth support professionals) to provide mental health support helps reduce anxiety and depression in pregnant and postpartum people. Researchers will compare 90 participants in Massachusetts whose doulas receive special mental health…

This study is testing whether mind-body practices like meditation can help reduce common Long COVID symptoms such as pain, fatigue, and shortness of breath. Researchers will compare two different mind-body programs against usual medical care in 180 adults who have had symptoms fo…

This study aims to find out if one of two commonly used pain and sedation medicines (fentanyl or hydromorphone) is better for adults in the ICU who need help breathing from a machine. Researchers will compare the drugs to see if one leads to patients needing less total medication…

This study is testing whether letting patients control their own level of nitrous oxide (laughing gas) during a vasectomy helps reduce pain and anxiety. 35 men scheduled for the procedure will use a remote to adjust the gas while staying awake. Researchers want to see if this sel…

This study is testing whether a treatment called dry needling can reduce pain from tight, tender spots in the shoulder and neck muscles, known as trigger points. Researchers will compare dry needling to a fake treatment in 70 adults to see if it helps. They will also use special …

This study is testing whether a gentle, non-invasive brain stimulation technique can help people who have trouble finding words after a traumatic brain injury (TBI). Researchers will use a special cap to deliver a tiny electrical current to specific brain areas involved in memory…

This study is testing whether mind-body therapy can help people with chronic back pain. Researchers will compare two different mind-body approaches against standard medical care to see which works best at reducing pain and improving daily function. The study aims to enroll 150 ad…

This study is testing whether injecting sterile salt water (saline) through a tiny spinal tube can help patients regain leg movement faster after knee or hip replacement surgery. Researchers are comparing patients who receive the saline injection to those who don't to see if it r…

This small pilot study is testing whether a mind-body therapy program can help people with long-term pain in their wrists, elbows, or shoulders from repetitive stress. Researchers will see if the program improves arm function, reduces pain intensity, and lowers pain-related anxie…

This study compares two ways to inject numbing medicine for wrist fractures. One method uses ultrasound to guide the needle, while the other is done by feel. Researchers want to see if using ultrasound helps provide better pain relief for adults when their broken wrist is being s…

This small, early-stage study is testing whether a mind-body intervention can help people with frequent migraines. Researchers are recruiting 10 adults to try the remote program and provide feedback. The main goal is to see if the approach is practical and to gather information f…

This study aims to understand the best blood pressure levels to maintain during surgery for optimal brain health in older adults. Researchers will monitor brain electrical activity and oxygen levels in 100 patients aged 60+ undergoing major non-cardiac surgery. The goal is to lea…

This study aims to understand why some women develop painful arm swelling (lymphedema) after breast cancer treatment while others don't. Researchers will use special imaging to map the lymphatic drainage pathways in the arms of healthy women and breast cancer survivors who avoide…

This study aims to understand how quickly water and a carbohydrate sports drink empty from the stomach of women in early labor. Researchers will compare women who have an epidural for pain relief to those who do not, using ultrasound to measure stomach volume over time. The goal …

This study aims to understand why some men with enlarged prostate (BPH) don't respond to the common medication Finasteride. Researchers will follow 120 men eligible for this treatment, using MRI scans and genetic analysis to look for markers that predict treatment resistance. The…

This study aims to understand what happens to the body, especially the kidneys, during heat stress. Healthy volunteers will exercise in a hot room under different conditions. Researchers will also test if taking vitamin B3 changes how the body responds to the heat.

This study aims to understand the early stages of psychotic disorders like schizophrenia and bipolar disorder. Researchers will collect information from 320 people recently diagnosed, including brain scans, eye movement tests, and genetic samples, to see if these biological marke…

This study is testing whether low-cost, single-use bronchoscopes are practical and safe for routine lung procedures. Twenty adult participants will have their lung procedure done with a disposable scope. Doctors will rate the disposable scope's performance and note if they need t…

This study aims to understand why postmenopausal women have a higher risk of developing a specific type of heart failure where the heart muscle is stiff. Researchers will analyze heart tissue samples from 500 women undergoing heart surgery to study how the loss of estrogen affect…

This study aims to understand the differences between brown fat, which burns energy, and white fat, which stores it. Researchers will collect small fat samples from 40 healthy adults and analyze them in a lab. The goal is to map how these fat types work, which could one day lead …

This study is investigating whether practicing a specific 21-minute meditation daily for 6 months leads to measurable changes in brain health. Researchers will compare 80 adults who meditate to a similar group who do not, using brain scans and other tests. The goal is to understa…