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IVF dilemma: should embryos be transferred earlier or later when you have few?

NCT ID NCT06746129

Knowledge-focused Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether transferring embryos after 3 days or 5 days leads to more live births in IVF patients who have 5 or fewer embryos. About 1,126 people will take part, and researchers will also track patient satisfaction and complications. The goal is to help doctors and patients make better decisions about when to transfer embryos.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 1,126 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Jun 2031

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 44 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * autologous IVF cycle * ≤5 zygotes on day 1 of development * Fresh embryo transfer Exclusion Criteria: * Planned preimplantation genetic testing (PGT) of all embryos * More than 2 previous IVF cycles * History of recurrent pregnancy loss (≥3) * Body mass index \>40 * Presence of uterine factor infertility * Planned gestational carrier * Endometrial lining \<6mm measured on the day of trigger * Lupron-only trigger, elevated progesterone in the fresh cycle (≥1.5ng/ml) * Delayed fertilization (\>18 hours) * Rescue intracytoplasmic sperm injection (following failed regular fertilization) * Use of non-ejaculated sperm (testicular sperm extraction) * Embryo transfer number outside American Society of Reproductive Medicine (ASRM) guidelines * Cycle is converted to a cycle in which all embryos are frozen

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Conditions

The condition(s) this trial relates to.

infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infertility (ivf patients)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Boston IVF

    RECRUITING

    Boston, Massachusetts, 02451, United States

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