New combo procedure aims to seal persistent lung air leaks without surgery
NCT ID NCT07184528
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This pilot study is testing whether combining a blood patch (using the patient's own blood) with a small valve can safely and effectively seal persistent air leaks in the lungs. These leaks often happen after lung surgery or injury and can lead to long hospital stays. The study will follow 20 adults who are not candidates for surgery to see if the procedure works and how quickly they recover.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- autologous blood and tranexamic acid (TXA)
- What this could lead to
- If successful, this combination procedure could offer a non-surgical option to seal persistent air leaks, potentially shortening hospital stays and improving recovery.
- What could go wrong
- This is a very small pilot study (20 people) with no control group, so results may not apply broadly. Risks include valve migration, new air leaks, or worsened lung function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Beth Isreal Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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