New probe aims to zap lung tumors through a scope

NCT ID NCT05281237

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a flexible microwave ablation probe that can be guided through a bronchoscope to destroy small lung cancer nodules (up to 3 cm) before surgical removal. Ten people with stage I-II lung cancer will receive the ablation during a bronchoscopy, and the treated tissue will be examined after surgery to see how much of the tumor was killed. The goal is to see if this less invasive approach is feasible and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AveCure flexible microwave ablation probe (device)
What this could lead to
If successful, this could offer a less invasive way to treat early-stage lung cancer by destroying tumors through a bronchoscope before surgery.
What could go wrong
This is a very small early feasibility study with only 10 participants, so results may not apply broadly. The procedure may not fully destroy the tumor or could cause side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02115, United States

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