Heart stent study aims to cut unnecessary procedures with a simple wire test

NCT ID NCT05491668

Recruiting now Diagnosis Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing whether a thin wire that measures blood flow in heart arteries can help doctors decide which blockages truly need a stent. About 107 people with severe-looking blockages will have the wire test before and after stent placement. The goal is to see if some blockages that look severe on an X-ray are actually not limiting blood flow, so stents could be safely avoided.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: OpSens OptoWire III (diagnostic wire)
What this could lead to: If successful, this could help doctors avoid unnecessary stents in patients whose blockages are not actually limiting blood flow, reducing risks and costs.
What could go wrong: This is a small, early-stage study (107 people) that only measures outcomes at 30 days. The wire may not change long-term outcomes, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

Locations

Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States

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