Heart stent study aims to cut unnecessary procedures with a simple wire test
NCT ID NCT05491668
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing whether a thin wire that measures blood flow in heart arteries can help doctors decide which blockages truly need a stent. About 107 people with severe-looking blockages will have the wire test before and after stent placement. The goal is to see if some blockages that look severe on an X-ray are actually not limiting blood flow, so stents could be safely avoided.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
OpSens OptoWire III (diagnostic wire)
What this could lead to
If successful, this could help doctors avoid unnecessary stents in patients whose blockages are not actually limiting blood flow, reducing risks and costs.
What could go wrong
This is a small, early-stage study (107 people) that only measures outcomes at 30 days. The wire may not change long-term outcomes, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••