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New handheld scanner could replace MRI for muscle disease monitoring

NCT ID NCT07502989

Diagnosis Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a handheld device called mScan that uses a tiny, painless electrical current to measure muscle health. Researchers want to see if it can give similar results to an MRI, but faster and more conveniently. The study involves 150 adults with and without muscle diseases like muscular dystrophy or myositis. If successful, the mScan could become a simple tool to track muscle health over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients Diagnosed with Myopathies and Healthy Controls

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Ages 18-89 * Evidence of a primary myopathic condition as determined by detailed chart review, including results of genetic testing, serological data, or previous muscle biopsy Exclusion Criteria: * Inability to lie flat or history of claustrophobia * \>1+ lower extremity edema * Presence of multiple other pathologies affecting lower extremity muscles to be studied * Pregnancy * Contraindications for MRI scanning - e.g. MRI incompatible pacemaker, deep brain stimulator, or lower extremity hardware * Contraindications to undergo DXA Scan * Any studies/scans with a radioisotope within the past 15 days * Any imaging with radiographic contrast in the past 7 days * Weight greater than 450 lbs * Calcium supplements or antacids containing calcium in the past 24 hours * Severe obesity with BMI \> 35 kg/m2, given difficulties fitting in MRI scanner and impact of severe obesity on EIM data * Chronic skin conditions with ulcerations which would interfere with EIM electrode contact or be uncomfortable for the participant

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Conditions

The condition(s) this trial relates to.

congenital myopathy Distal Myopathies distal myopathy juvenile dermatomyositis muscle tissue disorder muscular dystrophy myofibrillar myopathy myopathy myositis disease Thomsen and Becker disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Congenital myopathy Distal myopathy Muscular dystrophies Myofibrillar myopathy Myopathies Myopathy Myositis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

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