Could a single workout shield damaged muscles? a new trial investigates
NCT ID NCT05599568
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study explores whether a single bout of exercise can protect against muscle damage from a later session—a phenomenon called the repeated bout effect—in people with neuromuscular diseases. Unlike healthy individuals, patients with these conditions may experience muscle damage even with concentric exercise, so the trial tests both concentric and eccentric exercise. Researchers will measure changes in creatine kinase levels after two exercise sessions to see if the protective effect occurs. The findings could help design safer, more effective exercise programs for people with myopathy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Exercise (concentric or eccentric)
- What this could lead to
- If the repeated bout effect occurs in neuromuscular diseases, it could inform safer exercise programs that reduce muscle damage and improve training benefits for patients.
- What could go wrong
- This is a small, early study (27 participants) and the effect may not appear in all patients or translate to real-world exercise. Exercise itself carries a risk of muscle damage in this population.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MYOPATHY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Neuromuscular Research Unit, 3342
Copenhagen, DK-2100, Denmark
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Continued anifrolumab treatment studied for lupus and related diseases
- Global study tracks rare muscle disease to pave way for future treatments
- Can Sauna-Like heat help chronic pain? new study investigates
- Mind-Reading device aims to give voice to the paralyzed
- Video games as therapy: VR shows promise for children with muscle disorders
- New handheld scanner could replace MRI for muscle disease monitoring