Could a Two-Drug combo beat standard care for BPH?

NCT ID NCT06944145

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding raloxifene to the standard drug finasteride works better than finasteride alone for men with an enlarged prostate (BPH). About 242 adults will take either the combo or finasteride plus a placebo for 12 months. The goal is to see if the combo improves urinary symptoms more than the single drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

finasteride and raloxifene

What this could lead to

If successful, this combination could offer a more effective treatment option for men with BPH who don't respond to finasteride alone.

What could go wrong

This is a mid-stage trial with 242 participants, so results may not apply to everyone. Adding raloxifene also carries risks like blood clots, which are already listed as an exclusion.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••