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Scientists map hidden lymphatic highways in Women's arms

NCT ID NCT05253352

Knowledge-focused Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses special imaging to map the lymphatic system in the arms of healthy women and breast cancer survivors who did not develop swelling (lymphedema). The goal is to learn how these alternate pathways work and why some people avoid lymphedema after lymph node removal. About 142 women will participate, helping researchers better understand the body's natural drainage routes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 142 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Women with a history of breast cancer treatment including axillary lymph node dissection (ALND) more than 2 years prior to study participation, who did not develop lymphedema.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female * History of breast cancer treatment including ALND - defined by removal of \>=10 lymph nodes - more than 2 years before study participation * Ability to understand the protocol and willingness to participate * At least 18 years of age Exclusion Criteria: * Prior history of bilateral lymph node surgery * Prior history of other surgical procedures of the affected upper extremity besides the axillary management for breast cancer treatment * Prior history of chronic inflammatory conditions (e.g. rheumatoid arthritis) * Prior history of filarial infections * Prior history of lymphedema * Patient-reported pregnancy * Patients who are breastfeeding * Iodine allergy * Prior history of upper extremity deep vein thrombosis * Prior history of congestive heart failure * Prior history of venous thoracic outlet syndrome * Current active cancer

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Conditions

The condition(s) this trial relates to.

breast cancer lymphatic system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lymphatic system

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

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