Cure My Disease

Don't miss your cure!

 Log in / Sign up

Two nerve blocks go Head-to-Head for mastectomy pain relief

NCT ID NCT06548646

NEW Symptom relief Sponsor: Safie ramez tewfeik abd el moneim Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 16, 2026 · Last updated Oct 16, 2026

Summary

Researchers compare two ultrasound-guided nerve blocks, the thoracic interfascial plane block and the erector spinae plane block, to see which controls pain better after modified radical mastectomy for breast cancer. The study enrolls 200 women aged 21 and older who are scheduled for this surgery. Participants receive one of the two blocks before surgery, and researchers track pain scores, pain medication use, side effects, recovery milestones, and long-term outcomes like persistent pain and quality of life over six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two ultrasound-guided nerve blocks: the thoracic interfascial plane block and the erector spinae plane block
What this could lead to
If one block proves better, it could become a standard option for managing pain after breast cancer surgery, possibly reducing reliance on opioids.
What could go wrong
This is a single-center study of 200 women, so results may not apply broadly. Nerve blocks can fail or cause temporary numbness, and long-term pain relief is not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

200 people

The number who actually took part.

Started

Nov 2024

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients older than 21 years old * American Society of Anesthesiologists (ASA) physical status II. Exclusion Criteria: * Known allergy to one of the study medications. * Skin infections at the site of the needle puncture. * Significant organ dysfunction (hepatic, renal, or cardiac dysfunction), coagulopathy or recent anticoagulant use, epilepsy. * Patients diagnosed with obstructive sleep apnoea, pulmonary compromise .

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Breast cancer are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain following modified radical mastectomy for breast cancer

Contacts and locations

Locations

  • Ainshams University Hospitals

    Cairo, Abbasiya, 1181, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.