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Can breast cancer surgery be done without general anesthesia? researchers test nerve blocks plus hypnosis

NCT ID NCT07877740

NEW Knowledge-focused Sponsor: Hôpital Fribourgeois Source: ClinicalTrials.gov ↗

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The trial has finished. Results may not be published yet.
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Cancelled before anyone took part.

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Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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First seen Oct 16, 2026 · Last updated Oct 16, 2026

Summary

Researchers at a Swiss hospital are studying whether a standardized locoregional anesthesia protocol can carry patients through breast cancer surgery without converting to general anesthesia. The protocol uses predefined ultrasound-guided fascial plane blocks, paired with either procedural sedation or adjunctive hypnosis. About 65 adults scheduled for elective unilateral breast cancer surgery will receive the protocol as part of routine care. The team will track how often surgery finishes without general anesthesia, along with patient acceptance, protocol adherence, induction time, satisfaction, and complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A standardized locoregional anesthesia protocol using ultrasound-guided fascial plane blocks, combined with procedural sedation or adjunctive hypnosis
What this could lead to
If the protocol proves workable, it could offer a way to perform breast cancer surgery without general anesthesia, which may suit patients who want to avoid it or cannot tolerate it.
What could go wrong
This is a small observational study at one hospital, so results may not carry over to other centers or surgeons. Some participants may still need conversion to general anesthesia, and the approach depends on operator skill and patient cooperation.

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Study facts

What this study's own registry entry says, in plain language.

Participants

About 65 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients scheduled for unilateral breast cancer surgery at HFR Fribourg during the study period.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Scheduled for elective unilateral breast cancer surgery (e.g. lumpectomy or mastectomy with or without sentinel lymph node biopsy or axillary dissection) Exclusion Criteria: * Contraindications to locoregional anesthesia (coagulopathy (INR \> 1.5, thrombocytes \< 80 000/mm³), infection at puncture site, allergy to local anesthetics) * Inability to cooperate with the procedure (e.g. major language barrier, severe uncontrolled psychiatric disorder or severe cognitive impairment) * Pregnancy

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Conditions

The condition(s) this trial relates to.

breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer surgery Fascial plane block Hypnosis Locoregional anaesthesia

How to take part

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  2. The official record

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Contacts and locations

Locations

  • Hôpital Fribourgeois

    Fribourg, Switzerland

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