Can MRI predict finasteride failure? new study seeks answers

NCT ID NCT04288427

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 37 times

Summary

This study aims to understand why some men with an enlarged prostate (BPH) do not respond to the common drug finasteride. Researchers will follow 120 men starting finasteride, tracking their symptoms and using MRI scans and genetic tests over three years. The goal is to find ways to predict resistance early, so non-responders can try other treatments sooner.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Finasteride

What this could lead to

If successful, this could help doctors identify non-responders to finasteride before treatment, saving time and offering alternative therapies sooner.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to a new therapy, and results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia Lower Urinary Tract Symptoms prostate disorder urinary system disorder urinary tract obstruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.