Can a fluid injection make prostate surgery safer and less bloody?

NCT ID NCT07749794

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether injecting a fluid mixture around the prostate before surgery can make the procedure easier and reduce bleeding. Men with enlarged prostates and moderate-to-severe urinary symptoms will be randomly assigned to either the new hydrodissection-assisted technique or the conventional surgery. The study will compare blood loss, operation time, and recovery outcomes to see if the new approach offers benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Hydrodissection-assisted bipolar prostatic enucleation-enucleoresection with subcapsular injection of diluted norepinephrine and methylene blue
What this could lead to
If successful, this technique could make prostate surgery safer and faster, with less bleeding and quicker recovery for men with enlarged prostates.
What could go wrong
This is a single-center trial with 100 participants, so results may not apply broadly. The injection adds complexity and could carry risks like infection or tissue damage.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia Lower Urinary Tract Symptoms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Benha University Hospital

    Banhā, Qalyubia Governorate, 13511, Egypt

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