Laser vs. traditional: which surgery eases prostate symptoms best?

NCT ID NCT07741214

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial compares two surgical procedures for men with an enlarged prostate causing urinary obstruction: low power HOLEP, which uses a laser, and TURP, a traditional cutting technique. The goal is to see which approach better relieves lower urinary tract symptoms, measured by changes in the International Prostate Symptom Score (IPSS). The study will enroll 100 men with obstructed flow due to BPH, randomly assigning them to one of the two procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
low power HOLEP (a laser-based surgical procedure) compared with TURP (a traditional surgical procedure)
What this could lead to
If low power HOLEP proves as effective as TURP, it could offer a less invasive surgical option for men with enlarged prostate, potentially with fewer side effects.
What could go wrong
This is a single trial with 100 participants, and results may not apply to all men. Surgical risks include bleeding, infection, or urinary issues, and the new technique might not be superior to the standard approach.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mohamed Fawzy Salman

    Cairo, Egypt

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