Urinary tract obstruction

This study looks at people with a sudden kidney blockage from a stone in their only working kidney. Doctors will randomly use either a tube placed through the bladder or one through the back to drain urine. The goal is to see which method helps kidney function recover better and …

This trial tests a procedure called fetal cystoscopy for unborn male babies with a severe blockage in the urinary tract (LUTO). Doctors insert a tiny telescope through the mother's belly into the baby's bladder to diagnose and treat the blockage with a laser. The study will enrol…

This study tests a step-by-step treatment plan for fetuses with lower urinary tract obstruction (LUTO), a condition where a blockage prevents urine from leaving the bladder. Doctors will use either a shunt to drain urine or a tiny scope to clear the blockage. The goal is to see i…

This study tests whether repeatedly injecting a sterile saltwater solution into the womb can help fetuses with severe kidney problems grow their lungs. Normally, these babies have too little amniotic fluid, which prevents the lungs from developing. The goal is to see if this proc…

This study is testing the NXT Urodynamics System, a device used to measure how well the bladder stores and releases urine. Researchers want to confirm it is safe and works correctly in people with bladder problems like incontinence or overactive bladder. About 180 adults who need…

This study looks at whether a special ultrasound technique called shear wave elastography can help doctors tell the difference between normal kidney swelling during pregnancy and swelling caused by a blockage that needs treatment. Researchers will measure kidney stiffness in 250 …

This study is testing whether an artificial intelligence (AI) system can accurately interpret ultrasound images of the heart and kidneys. Researchers will enroll 300 patients receiving these scans and compare the AI's readings to standard interpretations. The goal is to improve h…

This study tests a new ultrasound technique that uses a contrast dye and special computer processing to create detailed images of blood flow and tiny blood vessels in the kidneys. It will involve 20 children aged 1 month to 6 years with congenital kidney and urinary tract abnorma…

This study tests whether putting a drug called aminophylline into the bladder before placing a ureteral stent helps doctors get the stent past a blocking stone more easily. The trial involves 72 adults with sudden kidney failure from stones in a single working kidney. Half get th…

This study tests a new type of ureteric stent designed to cause fewer blockages, infections, and less pain than standard stents. About 50 adults who have had stents before for kidney stones or cancer will try the new stent. The goal is to see if it reduces complications and the n…

This study tests whether letting a bladder catheter fall out on its own (passive removal) is better than having a nurse pull it out (active removal) after urological surgery. 160 men will be randomly assigned to one method. Researchers will measure satisfaction, pain, and anxiety…

This study looks at whether a special ultrasound technique, called shear wave elastography, can predict how well a child's kidney will recover after surgery to fix a blockage. Researchers will measure kidney stiffness before and after surgery in 84 children aged 6 months to 18 ye…

This study tests a new method to help patients understand complex spine or prostate surgeries before they agree to them. Instead of just reading a form, patients watch multimedia content and answer questions to check their understanding. The goal is to see if this approach makes …

This study looks at how well three AI models—ChatGPT, Gemini, and Deepseek—can diagnose and suggest treatments for urology diseases. Researchers will use 800 past patient records from four hospitals to check the AI's accuracy and usefulness. The goal is to understand if AI can he…

This study aims to understand why some men with an enlarged prostate (BPH) do not respond to the common drug finasteride. Researchers will follow 120 men starting finasteride, tracking their symptoms and using MRI scans and genetic tests over three years. The goal is to find ways…