Urinary tract obstruction
MONDO:0003330Blockage of the normal flow of contents of the urinary tract.
Also known as: obstructive uropathy, urinary obstruction
27 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Experimental fetal fluid therapy aims to save babies born without kidneys
Disease control CompletedThis trial tests whether repeatedly adding sterile fluid into the womb can help fetuses with severe kidney failure grow enough lungs to survive after birth. Pregnant women with early pregnancy kidney failure can choose to receive the infusions or just be monitored. Babies who sur…
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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New stent aims to ease chronic ureter blockages
Disease control CompletedThis study tested a special stent called MEMOKATH 051 in 13 adults with long-term ureter blockages who usually need a standard double J stent. The goal was to see how long the new stent lasts and how well it is tolerated over 3 years. Participants had the new stent placed during …
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Could a simple ultrasound replace radiation scans for kidney blockages?
Diagnosis CompletedThis study tested whether a special ultrasound with a contrast dye (Definity) can detect kidney obstructions. Ten adults with a blocked kidney had ultrasound scans before and after surgery to relieve the blockage. The goal was to see if this method works as well as standard nucle…
Phase: PHASE2 • Sponsor: University of Michigan • Aim: Diagnosis
Last updated Jun 27, 2026 07:52 UTC
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Barbed sutures may speed up kidney surgery, small trial suggests
Symptom relief CompletedThis study tested whether barbed sutures (V-Loc) are safer and easier to use than standard polyglactin sutures (Vicryl) in minimally invasive kidney surgery for a blocked ureter. Forty adults aged 18 to 60 were randomly assigned to receive either barbed or standard sutures during…
Phase: PHASE3 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Magnetic stent removal spares kids from anesthesia
Symptom relief CompletedThis study tested a special ureteral stent with a magnetic end in 67 children with urinary tract problems or kidney transplants. The goal was to see if the stent could be removed without general anesthesia, using a magnetic catheter instead. The approach aims to make the removal …
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Antibiotics before kidney drainage: help or hype?
Knowledge-focused CompletedThis study looked at whether giving antibiotics before a kidney drainage procedure (called percutaneous nephrostomy) prevents urinary tract infections in cancer patients whose urinary tract is blocked by a tumor. Researchers reviewed records of 320 cancer patients who had the pro…
Sponsor: Barretos Cancer Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Stent registry shows Real-World results for blocked ureters
Knowledge-focused CompletedThis completed registry followed 379 people who received a Boston Scientific ureteral stent to treat a blocked ureter. The goal was to see how well the stent worked and if it caused any serious side effects. Patients also reported on their quality of life. The study provides real…
Sponsor: Boston Scientific Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Fetal surgery immune mystery: why do some babies arrive too early?
Knowledge-focused CompletedThis study looked at 21 pregnant women and their babies to understand how surgery before birth changes the immune system. The goal was to find out if immune system activation might cause early labor. Researchers collected blood samples and studied the placenta to track immune cha…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC