Could a simple ultrasound replace radiation scans for kidney blockages?

NCT ID NCT05090800

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special ultrasound with a contrast dye (Definity) can detect kidney obstructions. Ten adults with a blocked kidney had ultrasound scans before and after surgery to relieve the blockage. The goal was to see if this method works as well as standard nuclear scans, but without radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Definity contrast agent (Perflutren Lipid Microsphere)
What this could lead to
If successful, this could provide a safer, radiation-free way to diagnose kidney obstructions using ultrasound instead of nuclear scans.
What could go wrong
This is a very small, early-phase study with only 10 participants, so results may not apply to everyone. The technique is still experimental for this use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States