Fetal surgery immune mystery: why do some babies come too early?

NCT ID NCT04484441

First seen Feb 15, 2026 · Last updated May 13, 2026 · Updated 12 times

Summary

This study looked at how surgery on unborn babies with birth defects like spina bifida affects the immune system of both the mother and the fetus. Researchers wanted to understand if immune system changes might cause some babies to be born too early. The study included 21 pregnant women and their babies, comparing those who had fetal surgery with those who did not.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Mayo Clinic in Rochester, Minnesota

    Rochester, Minnesota, 55905, United States

  • University of Texas Houston

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.