Which stent graft shrinks aneurysms best? new trial aims to find out.

NCT ID NCT05378347

Recruiting now Disease control Sponsor: Medtronic Cardiovascular Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study compares two medical devices (Endurant and Excluder stent grafts) used to treat abdominal aortic aneurysms—a bulging blood vessel in the belly that can be life-threatening if it bursts. About 600 people with large aneurysms will be randomly assigned to get one of the two devices. The main goal is to see which device leads to more shrinkage of the aneurysm one year after the procedure.

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Conditions

The condition(s) this trial relates to.

abdominal aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL AORTIC ANEURYSM ABDOMINAL AORTIC ANEURYSM >= 5.0 CENTIMETERS IN FEMALE (DISORDER) ABDOMINAL AORTIC ANEURYSM >= 5.5 CENTIMETERS IN MALE (DISORDER)

Contacts and locations

Locations

AOU Citta della Salute e della Scienza di Torino
RECRUITING

Torino, 10126, Italy
Albany Medical College
WITHDRAWN

Albany, New York, 12208, United States
Amsterdam University Medical Center
RECRUITING

Amsterdam, Netherlands
Asahikawa Medical University Hospital
RECRUITING

Asahikawa, Hokkaido, 078-8510, Japan
Ascension Via Christi Saint Francis
RECRUITING

Wichita, Kansas, 67214, United States
Assistance Publique - Hopitaux de Marseille Hopital de la Timone
RECRUITING

Marseille, Marseille Cedex, 13385, France
Azienda Ospedaliera Universitaria Federico II
RECRUITING

Naples, 80131, Italy
Baystate Medical Center
RECRUITING

Springfield, Massachusetts, 01199, United States
Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States
CHU Clermont-Ferrand
RECRUITING

Clermont-Ferrand, 63003, France
Cardiovascular Surgery Clinic
WITHDRAWN

Memphis, Tennessee, 38120, United States
Catharina Ziekenhuis
RECRUITING

Eindhoven, 5623 EJ, Netherlands
Centre Hospitalier Universitaire Vaudois
RECRUITING

Lausanne, 1011, Switzerland
Chi Mei Medical Center
RECRUITING

Tainan, 710402, Taiwan
China Medical University Hospital
RECRUITING

Taichung, 404327, Taiwan
Denver Health Medical Center
RECRUITING

Denver, Colorado, 80204, United States
Elisabeth Hospital Essen
RECRUITING

Essen, 45138, Germany
Erasmus Medisch Centrum
RECRUITING

Rotterdam, 3015 GD, Netherlands
Fondazione IRCCS Ca' Granda - Ospendale Maggiore Policlinico
RECRUITING

Milan, 20122, Italy
Hamamatsu University Hospital
RECRUITING

Hamamatsu, Shizuoka, 431-3125, Japan
Helsinki University Hospital
RECRUITING

Helsinki, 00290, Finland
Hoag Hospital
RECRUITING

Newport Beach, California, 92663, United States
Hopital de Hautepierre - CHU de Strasbourg
RECRUITING

Strasbourg, 67200, France
Hospices Civils de Lyon-CHU Lyon
WITHDRAWN

Lyon, 69002, France
Hospital Universitario Son Espases
RECRUITING

Palma, Mallorca, 07210, Spain
Hospital of the University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Keio University Hospital
RECRUITING

Shinjuku-Ku, Tokyo, 160-0016, Japan
Kuopio University Hospital
RECRUITING

Kuopio, 70200, Finland
Loma Linda University Medical Center
RECRUITING

Loma Linda, California, 92354, United States
Luzerner Kantonsspital
RECRUITING

Lucerne, 6000, Switzerland
Maine Medical Center
RECRUITING

Portland, Maine, 04102, United States
Mayo Clinic Jacksonville
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic Rochester
RECRUITING

Rochester, Minnesota, 55905, United States
Medstar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Minneapolis Heart Institute Foundation
RECRUITING

Minneapolis, Minnesota, 55407, United States
Nagoya University Hospital
RECRUITING

Nagoya, Aichi-ken, 466-8560, Japan
National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan
Niigata University Medical and Dental Hospital
RECRUITING

Chuo Ku, Niigata, 951-8510, Japan
Northshore University Health System
RECRUITING

Skokie, Illinois, 60076, United States
Northside Hospital Forsyth
RECRUITING

Atlanta, Georgia, 30342, United States
Northwell Health Lenox Hill Hospital
RECRUITING

New York, New York, 10075, United States
Novant Health Forsyth Medical Center
RECRUITING

Winston-Salem, North Carolina, 27103, United States
Osaka Keisatsu Hospital
RECRUITING

Osaka, 543-8922, Japan
Oxford University Hospitals NHS Trust - John Radcliffe Hospital
RECRUITING

Oxford, Oxfordshire, OX3 9DU, United Kingdom
Prisma Health
WITHDRAWN

Greenville, South Carolina, 29615, United States
Rijnstate Hospital
RECRUITING

Arnhem, The Netherlands, 6815 AD, Netherlands
Royal Infirmary of Edinburgh
RECRUITING

Edinburgh, EH16 4SA, United Kingdom
Sarasota Memorial Hospital
RECRUITING

Sarasota, Florida, 34239, United States
St. Franziskus Hospital Munster
RECRUITING

Münster, 48145, Germany
Taipei Veterans General Hospital
RECRUITING

Taipei, 112201, Taiwan
The Heart Hospital Baylor Plano
RECRUITING

Plano, Texas, 75093, United States
Universitatsklinikum Frankfurt
RECRUITING

Frankfurt, 60590, Germany
University Hospital Augsburg
RECRUITING

Augsburg, 86156, Germany
University Hospital Cologne
RECRUITING

Cologne, 50937, Germany
University Hospital Leipzig
RECRUITING

Leipzig, 04103, Germany
University Hospital of Larisa
RECRUITING

Larissa, 41110, Greece
University Hospital rechts der Isar of the Technical University Munich
RECRUITING

Munich, 81675, Germany
University Hospitals, Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of California Davis Medical Center
WITHDRAWN

Sacramento, California, 95817, United States
University of California Irvine Medical Center
RECRUITING

Orange, California, 92868, United States
University of California San Francisco UCSF Medical Center
RECRUITING

San Francisco, California, 94143, United States
University of Kentucky
RECRUITING

Lexington, Kentucky, 40536, United States
University of Pittsburgh Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States
University of Virginia Health System
RECRUITING

Charlottesville, Virginia, 22908, United States
VA Maryland Health Care System
RECRUITING

Baltimore, Maryland, 21201, United States
Westchester Medical Center
RECRUITING

Valhalla, New York, 10595, United States
Yale Center for Clinical Investigation
RECRUITING

New Haven, Connecticut, 06519, United States

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