ARTERIAL STIFFNESS

This study is testing whether eating freeze-dried wild blueberry powder every day for six months can help control high blood pressure, improve gut bacteria, and enhance memory and thinking skills. It will involve 40 Black and White adults aged 45-65 who have elevated blood pressu…

This study is testing if a medication called empagliflozin, usually used for diabetes, can make stiff arteries more flexible in healthy older adults. It will involve 80 men and women aged 60-80 who already have some artery stiffening but do not have diabetes. Participants will ta…

This study is testing whether a combination of high-intensity interval training (short, very hard bursts of exercise) and the DASH diet (a diet known to lower blood pressure) can improve artery stiffness in people with high blood pressure. Researchers will recruit 20 adults aged …

This study is testing whether a drug called dapagliflozin can protect the heart from damage caused by a common type of breast cancer chemotherapy. About 100 women receiving anthracycline chemotherapy will take either dapagliflozin or a placebo pill daily during treatment. Researc…

This study is testing whether arm-based aerobic exercise can improve artery health and reduce heart disease risk in women who have completed breast cancer treatment. Researchers will measure artery stiffness and exercise capacity in 18 participants before and after an exercise tr…

This study is testing whether vitamin K2 supplements can help reduce how often people get migraines and make them less severe. Researchers will give 160 adults with frequent migraines either vitamin K2 or a placebo pill for six months to compare results. They're focusing on vitam…

This study follows 7,500 healthy volunteers for 12-16 years to understand how arteries naturally stiffen with age. Researchers use ultrasound scans to measure artery changes over time and identify which factors predict future heart problems. The goal is to better understand cardi…

This study aims to better understand how high levels of a specific blood fat called Lipoprotein(a), or Lp(a), affect the stiffness of arteries and the function of the heart over time. Researchers will observe 300 adults for one year, measuring artery health, heart function, and t…

This study aims to understand how testosterone and estrogen affect the body during gender-affirming hormone therapy. Researchers will observe 80 transgender participants and a control group for five years, measuring changes in metabolism, eating habits, weight, and heart health. …

This study aims to understand how CADASIL, a genetic disorder that damages small blood vessels and can lead to strokes and dementia, changes over time. Researchers will follow about 100 people with CADASIL and 40 healthy volunteers for 9 years, performing detailed tests on their …

This study aims to understand how blood pressure and artery stiffness change between day and night in people at high risk for heart disease, including those with kidney problems. Researchers will measure these patterns in 120 participants over 24 hours on two separate occasions. …