ARTERIAL STIFFNESS

This study looks at whether a daily dose of freeze-dried wild blueberry powder can improve blood sugar, blood pressure, and thinking skills in women aged 20-65 who have prediabetes and are overweight. Researchers will also check if it changes gut bacteria. The goal is to see if t…

This study looks at whether eating wild blueberries can improve heart health, thinking skills, and gut bacteria in adults aged 45-65 with high blood pressure. Researchers will measure blood pressure, artery stiffness, and memory over time. The goal is to see if a simple diet chan…

This study tests whether a daily pill called empagliflozin (a type of SGLT2 inhibitor) can reduce stiffening of arteries that happens with age. The trial will include 80 healthy adults aged 60-80 who have some artery stiffness but no diabetes. Participants will take the drug or a…

This study tests whether eating grapes every day can improve gut health, reduce inflammation, and help blood vessels work better in healthy overweight adults aged 45 to 70. Participants will drink a grape powder or placebo drink twice daily for three weeks. Researchers will measu…

This study tests whether dapagliflozin, a drug used for diabetes, can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. About 100 women will receive either dapagliflozin or a placebo daily during their chemo. Researchers will monitor heart funct…

This study tests whether taking vitamin K2 supplements for 6 months can lower the number of migraine days in adults with episodic migraine. Researchers will also measure if it improves blood vessel stiffness, which is often higher in people with migraines. About 160 participants …

This study looks at how testosterone and estrogen change eating habits, metabolism, energy use, and heart health in transgender people receiving hormone therapy. Researchers will track 80 participants over time to understand these effects. The goal is to learn more about how sex …

This study looks at how a specific blood fat called lipoprotein(a) might affect the stiffness of arteries, the health of blood vessel linings, and the heart's ability to pump. Researchers will follow 300 adults aged 18-75 for one year, measuring these factors and tracking any hea…

This study follows 155 adults with CADASIL, a genetic condition that narrows small blood vessels and can lead to strokes and dementia, over 9 years. Researchers will track changes in blood flow, brain structure, and thinking abilities through regular tests and samples. The goal i…

This study follows 7,500 adults over 12 to 16 years to see how their arteries change with age and how that affects their risk of heart disease and stroke. Researchers will use advanced ultrasound to measure artery stiffness and thickness. No treatments or medications are given—th…

This study looks at whether upper-body aerobic exercise can reduce artery stiffness caused by cancer treatments in women with breast cancer. Researchers will measure blood vessel health in 18 women aged 40-69 who are at least 15 months past surgery. The goal is to understand if e…

This study looks at how blood pressure and artery stiffness change between day and night in people at higher risk for heart disease, including those with kidney problems. Researchers will monitor 120 participants over 24 hours using wearable devices and collect blood and urine sa…