Scientists launch Decade-Long quest to unravel rare stroke disorder
NCT ID NCT05072483
First seen Jun 24, 2026 · Last updated Aug 04, 2026 · Updated 8 times
Summary
This study follows 155 adults with CADASIL, a genetic condition that narrows small blood vessels and raises the risk of strokes and dementia, over nine years. Researchers will use brain scans, blood tests, and other exams to track how the disease changes blood vessels and thinking abilities. Healthy volunteers also participate for comparison. The goal is to better understand the disease's progression, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal how CADASIL progresses, pointing toward future treatments or ways to monitor the disease.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly benefit participants and may not lead to immediate therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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