Could a common diabetes pill unstiffen aging arteries?
NCT ID NCT06506422
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether empagliflozin, a drug currently used for diabetes, can reverse the natural stiffening of arteries that happens with age. Researchers will give 80 healthy adults aged 60-80 either the drug or a placebo daily for 12 weeks. The main goal is to see if artery stiffness, measured by a standard test, improves.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Empagliflozin (a diabetes drug, here tested for artery health)
What this could lead to
If it works, this could point toward a simple daily pill to reduce artery stiffness and potentially lower heart risks in older adults.
What could go wrong
This is an early-phase study with only 80 people, so results may not apply widely. The drug is already used for diabetes, but its effect on artery stiffness in non-diabetic people is unproven.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Missouri
RECRUITINGColumbia, Missouri, 65211, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••