Iron showdown: IV vs pills for anemia after gastric bypass
NCT ID NCT04268849
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether intravenous iron works better than oral iron pills for treating iron deficiency anemia in people who have had gastric bypass or sleeve gastrectomy surgery. About 104 participants will be randomly assigned to receive either a single IV dose of ferumoxytol or daily oral ferrous sulfate. The main goal is to see which treatment improves hemoglobin levels and overall well-being more quickly, with results checked at 6 weeks and again at 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ferumoxytol (intravenous iron) and ferrous sulfate (oral iron)
- What this could lead to
- If IV iron proves more effective, it could become the preferred treatment for iron deficiency anemia after bariatric surgery, offering faster relief with fewer side effects.
- What could go wrong
- This is a relatively small trial (104 people) and results may not apply to all patients. Oral iron is the current standard, and IV iron carries rare risks like allergic reactions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Auerbach Hematology and Oncology
RECRUITINGBaltimore, Maryland, 21237, United States
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