Could a daily probiotic prevent iron deficiency in pregnancy?

NCT ID NCT07076849

Recruiting now Prevention Sponsor: University of Illinois at Chicago Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a probiotic called LP299V can help pregnant women at risk of iron deficiency absorb more iron from their diet. Researchers will give 250 women either the probiotic or a placebo from early pregnancy until labor. The goal is to see if the probiotic improves iron levels in the mother and baby, and reduces complications like anemia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lactiplantibacillus plantarum 299v (probiotic)
What this could lead to: If it works, this could offer a safe, low-cost way to prevent iron deficiency anemia in pregnant women, reducing risks for both mother and baby.
What could go wrong: This is a Phase 2 trial with 250 participants, so results are still early. The probiotic may not improve iron absorption enough to make a difference, and individual responses can vary.

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Conditions

The condition(s) this trial relates to.

Iron Deficiencies iron deficiency anemia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRON DEFICIENCY (ID) PREGNANCY

Contacts and locations

Locations

University of Illinois at Chicago
RECRUITING

Chicago, Illinois, 60612, United States

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