Can milk proteins stop deadly diarrhea cycles in malnourished kids?
NCT ID NCT05519254
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether daily supplements of lactoferrin and lysozyme, proteins found in milk, can prevent severe diarrhea and improve nutrition in children aged 6-24 months who were hospitalized with diarrhea and malnutrition. Six hundred children in Kenya will receive one of three supplements or a placebo mixed into their food for 6 months. Researchers will track diarrhea episodes and nutritional recovery to see if these natural proteins help break the cycle of illness and wasting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lactoferrin and lysozyme (milk proteins)
- What this could lead to
- If it works, this could provide a simple, affordable supplement to prevent repeated diarrhea and improve growth in malnourished children.
- What could go wrong
- This is a large phase 3 trial, but supplements may not work better than standard care. The study only follows children for 6 months, so long-term effects are unknown.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Homa Bay County Referral Hospital
RECRUITINGHoma Bay, Kenya
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Isebania Sub-County Hospital
RECRUITINGIsibania, Kenya
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Kisii Teaching and Referral Hospital
RECRUITINGKisii, Kenya
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Rongo Sub-County Hospital
RECRUITINGRongo, Kenya
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