Can milk proteins stop deadly diarrhea cycles in malnourished kids?

NCT ID NCT05519254

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether daily supplements of lactoferrin and lysozyme, proteins found in milk, can prevent severe diarrhea and improve nutrition in children aged 6-24 months who were hospitalized with diarrhea and malnutrition. Six hundred children in Kenya will receive one of three supplements or a placebo mixed into their food for 6 months. Researchers will track diarrhea episodes and nutritional recovery to see if these natural proteins help break the cycle of illness and wasting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
lactoferrin and lysozyme (milk proteins)
What this could lead to
If it works, this could provide a simple, affordable supplement to prevent repeated diarrhea and improve growth in malnourished children.
What could go wrong
This is a large phase 3 trial, but supplements may not work better than standard care. The study only follows children for 6 months, so long-term effects are unknown.

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Conditions

The condition(s) this trial relates to.

Cachexia Child Nutrition Disorders diarrheal disease nutritional deficiency disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Homa Bay County Referral Hospital

    RECRUITING

    Homa Bay, Kenya

  • Isebania Sub-County Hospital

    RECRUITING

    Isibania, Kenya

  • Kisii Teaching and Referral Hospital

    RECRUITING

    Kisii, Kenya

  • Rongo Sub-County Hospital

    RECRUITING

    Rongo, Kenya

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