New injection could fix nutrient deficiency in intestinal failure patients

NCT ID NCT06910943

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tests an injection of choline chloride in adolescents and adults with intestinal failure who rely on long-term intravenous nutrition. The goal is to see if the drug can safely raise choline levels and reduce liver injury. About 129 participants will receive either a low or high dose of the drug or a placebo, with an open-label extension for all.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aalborg University Hospital, Department of Medical Gastroenterology

    RECRUITING

    Aalborg, 9100, Denmark

    Contact

  • Beaujon Hospital - APHP

    NOT_YET_RECRUITING

    Clichy, 92110, France

    Contact

  • CHRU Nancy - Barbois Hospital

    NOT_YET_RECRUITING

    Vandœuvre-lès-Nancy, 54511, France

    Contact

  • Charite - University Hospital Berlin

    RECRUITING

    Berlin, 13353, Germany

    Contact

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

  • Columbia University Medical Center/ New York Presbyterian Hospital

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

    Contact

  • Czerniakowski Hospital Sp. z o.o. (LCC)

    RECRUITING

    Warsaw, 00-739, Poland

    Contact

  • Duke Clinic - Abdominal Transplant Research Office

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

  • Floridian Clinical Research

    RECRUITING

    Miami Lakes, Florida, 33016, United States

    Contact

  • M. Pirogow Provincial Specialized Hospital in Lodz, Nutritional Treatment Center

    RECRUITING

    Lodz, 90-532, Poland

    Contact

  • Nebraska Medicine

    NOT_YET_RECRUITING

    Omaha, Nebraska, 68105, United States

    Contact

  • Pinnacle Clinical Research- San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

  • Rennes University Hospital Center - Pontchaillou Site

    NOT_YET_RECRUITING

    Rennes, 35000, France

    Contact

  • Rigshospitalet - University Hospital Copenhagen

    RECRUITING

    Copenhagen, 2100, Denmark

    Contact

  • University Duisburg-Essen, University Hospital Essen

    NOT_YET_RECRUITING

    Essen, 45147, Germany

    Contact

  • University Hospitals Leuven, Campus Gasthuisberg

    RECRUITING

    Leuven, 3000, Belgium

    Contact

  • University of Colorado School of Medicine

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

Conditions

Explore the condition pages connected to this study.