Muscle loss in intestinal failure: could a simple protein and workout combo turn the tide?

NCT ID NCT07759271

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether adding whey protein supplements, resistance training, or both can improve muscle mass in adults with chronic intestinal failure and low muscle mass. Participants receive standard nutritional support and are randomly assigned to one of four groups: usual care, whey protein alone, resistance training alone, or the combination. Over six weeks, researchers track changes in muscle mass, strength, walking speed, and quality of life to see if these simple interventions can help.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
whey protein supplementation and resistance training
What this could lead to
If effective, this combination could offer a practical, non-drug way to preserve or build muscle in people with intestinal failure, improving strength and quality of life.
What could go wrong
The trial is small and short-term, so benefits may be modest or not lasting. Some participants may find the training or protein supplement difficult to tolerate.

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Conditions

The condition(s) this trial relates to.

chronic intestinal failure Intestinal Failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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Other studies related to the condition(s) this trial covers.