Baking soda in catheters may cut infections in kids with gut failure

NCT ID NCT05813535

Completed Disease control Sponsor: Riad Rahhal Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small study tested whether filling central catheters with sodium bicarbonate (baking soda) when not in use could prevent infections in children with intestinal failure. Six children participated, and the study looked at how many catheter-related bloodstream infections occurred. The approach is simple and inexpensive, but the tiny size means results are very preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sodium bicarbonate
What this could lead to: If it works, this could offer a simple, low-cost way to reduce dangerous catheter infections in children with intestinal failure.
What could go wrong: This is a very small completed Phase 2 trial with only 6 participants, so results may not apply broadly. The approach may not prove effective in larger studies.

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Conditions

The condition(s) this trial relates to.

chronic intestinal failure Intestinal Failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRBSI - CATHETER RELATED BLOODSTREAM INFECTION INTESTINAL FAILURE

Contacts and locations

Locations

University of Iowa

Iowa City, Iowa, 52242, United States

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