Newborn infection shield: taurolidine lock tested in 576 babies
NCT ID NCT07585188
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a taurolidine lock solution, placed inside central catheters, can prevent bloodstream infections in newborns. About 576 infants with central lines will receive either the taurolidine lock or a saline lock every 48 hours. The goal is to see if this approach reduces infection rates without causing catheter blockages.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- taurolidine 2% lock solution
- What this could lead to
- If it works, this could provide a safe way to prevent dangerous bloodstream infections in vulnerable newborns with central lines.
- What could go wrong
- This is an early-stage trial with no results yet. The lock solution may not reduce infections and could cause catheter blockages in very small catheters.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sant'Anna Hospital, University of Turin
Turin, 10126, Italy
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