Choline deficiency disease
MONDO:0004575A condition produced by a deficiency of choline in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
8 clinical trials for this condition and its sub-types.
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New injection aims to fix choline deficiency in intestinal failure patients
Disease control Recruiting nowThis study tests an injectable form of choline, a nutrient often missing in people with intestinal failure who rely on IV nutrition. The goal is to see if it can safely raise choline levels and reduce liver injury. About 129 adolescents and adults will receive either a low or hig…
Phase: PHASE2, PHASE3 • Sponsor: Protara Therapeutics • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Can a High-Calorie drink help malnourished kids grow?
Disease control Recruiting nowThis study tests whether daily high-calorie nutritional supplements can improve growth and development in 200 malnourished children aged 1 to 3 years. One group gets the supplements plus nutrition education, while the other gets only education and diet advice. Researchers will me…
Phase: NA • Sponsor: Children's Hospital of Chongqing Medical University • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Could a smaller dose of nutrients protect kids from malnutrition?
Prevention Recruiting nowThis study compares two types of nutrient supplements—small-quantity and medium-quantity—to see if the smaller one works just as well at preventing undernutrition in children aged 6 to 12 months. About 980 infants in Pakistan will receive one of the two supplements daily for 6 mo…
Phase: NA • Sponsor: Aga Khan University • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC