Scurvy
MONDO:0009412A condition that develops in people who do not consume an adequate amount of vitamin C in their diet. Although scurvy is relatively rare in the United States, it continues to be a problem in malnourished populations around the world (such as impoverished, underdeveloped third world countries). Early features of the condition include general weakness, fatigue and aching limbs. If left untreated, more serious problems can develop such as anemia, gum disease, and skin hemorrhages. Symptoms generally develop after at least 3 months of severe or total vitamin C deficiency. Scurvy can be cured with vitamin C supplements taken by mouth. Once recovery is complete, dietary modifications to ensure the 'recommended daily intake' of vitamin C is reached will prevent relapse. Except in the case of severe dental disease, permanent damage from scurvy does not usually occur.
Also known as: ascorbic acid deficiency, deficiency of vitamin C, scurvy, vitamin C deficiency, Gulo, nonfunctional, L-gulonolactone oxidase pseudogene, L-gulonolactone oxidase, nonfunctional, hypoascorbemia
29 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
New bone marrow transplant trial offers hope for kids with severe blood disorders
Disease control Recruiting nowThis study tests a bone marrow transplant from a family donor for children under 21 with severe non-cancer blood disorders like sickle cell disease, bone marrow failure, or immune problems. The goal is to see if the transplant can replace the diseased cells with healthy donor cel…
Phase: PHASE1, PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
-
Can a High-Calorie drink help malnourished kids grow?
Disease control Recruiting nowThis study tests whether daily high-calorie nutritional supplements can improve growth and development in 200 malnourished children aged 1 to 3 years. One group gets the supplements plus nutrition education, while the other gets only education and diet advice. Researchers will me…
Phase: NA • Sponsor: Children's Hospital of Chongqing Medical University • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
-
Could vitamin c help kids with severe pneumonia go home sooner?
Disease control Recruiting nowThis study looks at whether giving vitamin C alongside standard hospital care can help children under five with severe pneumonia recover faster. Ninety children will be split into two groups: one gets standard treatment alone, the other gets standard treatment plus a daily dose o…
Phase: PHASE4 • Sponsor: Children's Hospital and Institute of Child Health, Multan • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
-
Could a smaller dose of nutrients protect kids from malnutrition?
Prevention Recruiting nowThis study compares two types of nutrient supplements—small-quantity and medium-quantity—to see if the smaller one works just as well at preventing undernutrition in children aged 6 to 12 months. About 980 infants in Pakistan will receive one of the two supplements daily for 6 mo…
Phase: NA • Sponsor: Aga Khan University • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
-
Vitamin c shots may replace the knife for dark gums
Symptom relief Recruiting nowThis study tests if injecting vitamin C and glutathione into dark gums can lighten them as well as surgery. About 30 adults with gum pigmentation will be randomly assigned to either injection or scalpel removal. The main goal is to see how much the color improves, and the study a…
Phase: PHASE2 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
-
Gene hunt in children could unlock secrets of rare metabolic diseases
Knowledge-focused Recruiting nowThis study looks at children with suspected or confirmed genetic and metabolic disorders to find new disease-causing gene mutations. Researchers will analyze blood samples for DNA and metabolites, and in some cases take a small skin sample. The goal is to better understand these …
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jul 03, 2026 23:00 UTC
-
Massive study aims to unlock genetic secrets of childhood hormone disorders
Knowledge-focused Recruiting nowThis study enrolls up to 15,000 children with known or suspected endocrine or metabolic disorders, along with their family members. Researchers will collect medical records, blood, saliva, and other samples to identify genetic changes linked to these conditions. The goal is to be…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
-
Cleveland clinic launches massive biorepository to unlock secrets of heart disease
Knowledge-focused Recruiting nowThis study is creating a large collection of blood, urine, stool, and heart tissue samples from 10,000 people with and without heart or metabolic conditions. The goal is to store these samples along with medical information to speed up future research into what causes these disea…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
-
Can a simple tool give kids a voice in their own transplant care?
Knowledge-focused Recruiting nowThis study tests a new communication tool called 'Let's Get REAL' that helps children and teens (ages 8-17) and their families talk together about stem cell transplant or cellular therapy decisions. The goal is to see if the tool is easy to use and helpful for families. About 60 …
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
-
MRI study seeks brain clues in metabolic disease
Knowledge-focused Recruiting nowThis study uses MRI scans to look for brain differences in people with metabolic diseases compared to healthy volunteers. Researchers will track changes over time and link them to body fat and other health measures. About 126 adults will take part at Ulm University Hospital. No d…
Sponsor: University of Ulm • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
-
10,000 volunteers join hunt for Aging's hidden clues
Knowledge-focused Recruiting nowThe SMILE study is tracking 10,000 adults aged 18 and older to see how sarcopenia (age-related muscle loss) and metabolic diseases like diabetes influence overall health and lifespan. Researchers will collect data from medical records, tests, and surveys over time. This is an obs…
Sponsor: RenJi Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
-
Can a High-Fat diet help kids with Tough-to-Treat conditions?
Knowledge-focused Recruiting nowThis study follows 100 children under 18 who are already on a ketogenic diet for conditions like drug-resistant epilepsy, autism, chronic migraine, or brain tumors. Researchers want to see if the diet supports healthy growth, improves symptoms, and boosts quality of life. The die…
Sponsor: Danone Nutricia SpA Società Benefit • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:44 UTC