New decision tool aims to catch childhood TB earlier in africa
NCT ID NCT06593080
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new way to help doctors in Mozambique and Zambia decide if a sick child has tuberculosis (TB). The approach uses simple checklists and decision guides, supported by a computer system, to improve diagnosis and treatment, especially for children with HIV or severe malnutrition. Over 30,000 children will take part, and the goal is to see if this tool helps more kids get the right TB treatment faster.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Treatment Decision Algorithms (TDA) and Clinical Decision Support System (CDSS)
What this could lead to
If successful, this could provide a practical, evidence-based way to diagnose and treat childhood TB more effectively in resource-limited settings, reducing deaths and severe illness.
What could go wrong
This is a large implementation study, not a drug trial, so it tests a process rather than a new treatment. Results may vary by location and depend on how well health workers adopt the new system.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Allessandras Urban Health Centre
RECRUITINGLuanshya, Copperbelt, Zambia
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Chaisa Urban Health Centre
RECRUITINGLuanshya, Copperbelt, Zambia
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Chawama Urban Health Centre
RECRUITINGChingola, Copperbelt, Zambia
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Chipepo Rural Health Centre
RECRUITINGChirundu, Southern Province, Zambia
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Chiwempala Urban Health Centre
RECRUITINGChingola, Copperbelt, Zambia
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Fisenge Urban Health Centre
RECRUITINGLuanshya, Copperbelt, Zambia
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Habulile Rural Health Centre
RECRUITINGKalomo, Southern Province, Zambia
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Hachipilika Rural Health Centre
RECRUITINGChirundu, Southern Province, Zambia
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Jamba Rural Health Centre
RECRUITINGChirundu, Southern Province, Zambia
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Kabundi East Urban Health Clinic
RECRUITINGChingola, Copperbelt, Zambia
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Kalomo District Hospital
RECRUITINGKalomo, Southern Province, Zambia
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Kalomo Urban Health Centre
RECRUITINGKalomo, Southern Province, Zambia
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Kapululira Rural Health Centre
RECRUITINGChirundu, Southern Province, Zambia
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Kasompe Urban Health Centre
RECRUITINGChingola, Copperbelt, Zambia
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Kawama Urban Health Centre
RECRUITINGLuanshya, Copperbelt, Zambia
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Lusitu Rural Health Centre
RECRUITINGChirundu, Southern Province, Zambia
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Malaika Urban Health Centre
RECRUITINGLuanshya, Copperbelt, Zambia
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Mawaya Urban Health Centre
RECRUITINGKalomo, Southern Province, Zambia
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Mikomfwa Urban Health Centre
RECRUITINGLuanshya, Copperbelt, Zambia
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Mtendere Mission Referal hospital
RECRUITINGChirundu, Southern Province, Zambia
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Muchinshi Rural Health Centre
RECRUITINGChingola, Copperbelt, Zambia
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Namwianga Urban Health Centre
RECRUITINGKalomo, Southern Province, Zambia
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Nchanga 1 Urban Health Centre
RECRUITINGChingola, Copperbelt, Zambia
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Nchanga North Referal Hospital
RECRUITINGChingola, Copperbelt, Zambia
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Nkandanzovu Rural Health Centre
RECRUITINGKalomo, Southern Province, Zambia
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Roan Antelope General Hospital
RECRUITINGLuanshya, Copperbelt, Zambia
Contact
Contact
Contact
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Siachitema Rural Health Centre
RECRUITINGKalomo, Southern Province, Zambia
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Sikoongo Rural Health Centre
RECRUITINGChirundu, Southern Province, Zambia
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Thomson District Hospital
RECRUITINGLuanshya, Copperbelt, Zambia